Biological age, system by system

Your body doesn't
age all at once.

The OrganAge™ platform turns routine bloodwork into a biological age reading for nine of the body's major systems — showing where you're tracking younger, older, or right on time.

OrganAge™ Coming Soon View a Sample Report

Use bloodwork you already have. No new draw or specialty test required.

HIPAA compliant Bank-level encryption
Heart
29 yrs
12 years younger
Immune
33 yrs
8 years younger
OrganAge™ Report · Estimated biological age
34
Chronological age 41 · 7 years younger
9organ systems, modeled independently
450,000UK Biobank adults in training
1 panelroutine blood panel, no specialty testing
Your labsuse results you already have
Biology is personal

Your biology is not one number.

The OrganAge™ report estimates biological age for nine body systems, revealing how different parts of you can run younger, older, or in step with your chronological age.

Compared with chronological age
Lung
Age 36
8 yrs younger
Immune
Age 44
3 yrs older
Heart
Age 39
6 yrs younger
Heart
Age 31
9 yrs younger
Kidney
Age 58
6 yrs younger
Brain
Age 34
7 yrs younger
Metabolic
Age 39
5 yrs younger
Lung
Age 33
9 yrs younger

Illustrative results shown. Individual estimates vary.

Systems medicine

Precision comes from reading
your biology as one system.

A single biomarker can shape how several systems age at once. Rather than reading each marker in isolation, or pinning it to a single system, Cosmica's systems-medicine approach integrates them together — interpreting every result in the context of the whole to maximize the precision and accuracy of your biological age estimates.

Interactive demo · scroll to explore · drag to rotate

Simplified for illustration. The full analysis models many more biomarkers than shown here.

Metabolic
Age 37
6 yrs younger
Why the OrganAge™ report

Know where your biology stands,
and what to focus on next.

Nine Systems, Not One Score

Shows how biological age estimates vary across nine body systems, not just one whole-body number.

Built From Routine Bloodwork

The OrganAge™ platform turns common clinical biomarkers into a biological age estimate for each system.

Grounded in Long-Term Outcomes

Developed using longitudinal health data to connect biomarker patterns with meaningful health outcomes.

Personalized Next Steps

Turn your results into clear priorities across nutrition, movement, sleep, and other modifiable factors.

Inside the OrganAge™ report

One body. Nine biological age estimates.

Each system is modeled independently, revealing differences a single whole-body score can miss.

OrganAge report — nine body systems

Each system is modeled independently.

01Heart
02Brain
03Lung
04Kidney
05Metabolic
06Immune
07Muscle
08Gut
09Mental
How it works

From routine bloodwork to a
clearer picture of your biology.

01

Routine bloodwork

Use lab results you already have.

02

OrganAge™ analysis

Common clinical biomarkers are processed through our validated models.

03

Nine-system profile

Receive a biological age estimate for each system.

04

Personalized priorities

Highlights which areas may be worth focusing on next.

Powered by OptimAge™
Sample OrganAge report cover
Your OrganAge™ report

Your biology, translated
into a report you can use.

  • Biological age across nine body systems, each compared with your chronological age.
  • Clear biomarker explanations, showing what contributed to each result.
  • Personalized priorities, across nutrition, movement, sleep, and other modifiable factors.

View a Sample OrganAge™ Report ↓

Personalized next steps

From biological insight
to a plan built for you.

Your OrganAge™ report identifies the systems aging fastest. The OptimAge™ recommendation engine then prioritizes those results, translating them into a ranked set of actions across nutrition, movement, and supplements.

Nutrition

Food recommendations prioritized for your organ-system profile.

Movement

Activities ranked by relevance to your biological profile.

Supplements

Compounds prioritized based on your results and biological pathways.

Recommendations are educational and should be considered alongside guidance from a qualified healthcare professional.

Powered by the OptimAge™ recommendation engine

Recommendations ranked for your biology.

Recommendations aren't drawn from your visible system-age results alone. The OptimAge™ recommendation engine reads your organ-system gene-expression profiles to map thousands of foods, activities, and compounds against the biological pathways most relevant to you — then returns a short, prioritized set of actions.

You Ranked Pathways Compounds
From insight to action

Know what to
focus on next.

Use your OrganAge™ results to identify the systems that may deserve more attention, and track how your estimates change when you test again.

Your OrganAge™ results
estimated age vs. chronological age
SystemEst. ageDifference
Heart2912 years younger
Immune338 years younger
Kidney465 years older
The science

Built around health outcomes,
not age alone.

The OrganAge™ models were trained on more than 450,000 adults in the UK Biobank and confirmed in an independent validation population, using routine clinical biomarkers linked to long-term health outcomes. The research reveals how biological age patterns differ across the body's systems — and how those differences relate to future health.

450,000+ adults
UK Biobank training cohort
Longitudinal data
Health outcomes tracked over time
Independent validation
Confirmed in a separate population
BaselineYear 2Year 4Year 6Year 8+
Health outcomes observed during follow-up Participants represented in the training data
Benchmark · C-index

Higher accuracy. Larger cohort.
Best-in-class precision.

OrganAge™ outperforms proteomic and epigenetic clocks across every organ system, with traditional labs as input.

N = 450,000
N = 45,000
N = 7,500
0.40.50.60.70.80.9
AcceptableGoodExcellent
Organ Systems
Organ Systems
Organ Systems
Clinical Labs | OrganAge™
Proteomics-based clocks
Epigenetics-based clocks

C-index = concordance for health-outcome prediction; higher is better. Per-organ-system benchmark across methods.

Nature Medicine · 2026

The science behind the OrganAge™ models

How biological age patterns differ across the body's systems — trained on 450,000+ UK Biobank adults and confirmed in an independent validation population.

Fuentealba et al. · Nature Medicine · 2026

Peer-reviewed · Nature Communications

The science behind OptimAge™

The peer-reviewed scientific foundation for the OptimAge™ recommendation engine.

Wu et al. · Nature Communications · 2024

View research →
“Longevity shouldn't take thousands of labs to understand. A focused panel of 33 biomarkers can establish a clear baseline and cut through the noise — turning healthy aging into something people can finally see, and act on.”
Dr. David Furman
Dr. David Furman
Founder & Chief Scientific Officer, Cosmica Biosciences
Buck Institute · Stanford University · Co-developer of iAge, an inflammatory aging clock
For clinics & platforms

Bring OrganAge™ reports to your patients and members.

Integrate through our API or partner portal using the routine bloodwork you already collect. Deliver biological age estimates across nine organ systems within your existing experience.

HIPAA-compliant infrastructure Encrypted in transit & at rest
Partner With Us →
Get started

See your biological age,
system by system.

Turn routine bloodwork you already have into biological age estimates across nine organ systems, and clear priorities for what to focus on next.

OrganAge™ Coming Soon View a Sample Report
HIPAA compliant Bank-level encryption You control your data

No new blood draw · Takes about two minutes